Kwv yees li ntawm lub sijhawm nyeem ntawv: 19 feeb

Introduction

Yog tias koj nyeem cov ntawv blog no, nws yuav yog vim koj twb xav tias lossis muaj kev kuaj mob me me (MCI). Qee qhov xwm txheej ntawm kev puas siab puas ntsws me me (MCI) yuav nres hauv kev loj hlob thiab tsis txav mus rau kev ua haujlwm tsis zoo ntawm qib kom ua tau raws li cov txheej txheem rau Dementia.

Mild Cognitive Impairment (MCI) yog dab tsi? Pib ntawm no:

Tab sis feem ntau ntawm Mild Cognitive Impairment (MCI) cov teeb meem yuav tshwm sim rau hauv dementias. Thiab txawm hais tias koj qhov kev nce qib neurodegenerative nres ntawm Mild Cognitive Impairment (MCI), cov tsos mob no cuam tshuam rau koj lub neej thiab koj txoj haujlwm zoo. Hmoov tsis zoo, tsis muaj kev kho mob tshwj xeeb rau hom kev paub txog kev poob qis hauv cov tshuaj tseem ceeb, muaj qhov tseeb, kev kho mob nrog kev tshawb fawb zoo pom los txhim kho kev ua haujlwm.

Yog li txawm hais tias koj xav kom koj lub hlwb rov qab los ntawm kev paub txog thaum ntxov poob rau hauv daim ntawv ntawm rov tshwm sim los yog mob hlwb pos huab thiab / los yog Mild Cognitive Impairment (MCI) cov tsos mob, los yog koj xav kom nres cov neurodegenerative kev loj hlob mus rau Alzheimer's los yog ib co lwm yam dementia, qhov no yog blog post rau koj. Tej zaum koj yuav tau nyeem cov ntawv blog no tsis yog vim koj raug kev txom nyem los ntawm cov tsos mob ntawm kev paub tsis meej tab sis vim tias koj tab tom tshawb nrhiav yuav pab tus neeg koj hlub. Thiab yog hais tias yog li ntawd, qhov no tseem yog blog ncej rau koj.

3 Yog vim li cas koj cov teeb meem nco yuav tsis zoo li qub thiab koj yuav ua li cas txog nws

Nws tuaj yeem muaj ntau yam uas ua rau kev nkag siab tsis zoo. Tab sis tsis txhob cia qhov ntawd cuam tshuam koj. Muaj thawj qhov chaw pib uas yuav txhim kho cov tsos mob thiab teeb tsa rau lwm qhov kev sim thiab kev txhim kho uas yuav tsum tau ua. Muaj ntau ntau yam uas mus tsis ncaj ncees lawm hauv lub hlwb nrog kev paub txog cov tsos mob. Hauv tsab xov xwm no, peb yuav tham txog ob txoj kev xav txog dab tsi mus tsis ncaj ncees lawm nrog qhov kuv xav tias yog cov pov thawj txaus ntshai heev. Tom qab ntawd peb yuav tham txog thawj kauj ruam zoo heev los pib hais txog nws thiab tom qab ntawd qhov kuv pom tias yuav ua haujlwm tau zoo hauv kuv txoj haujlwm ua tus kws pab tswv yim kev puas siab puas ntsws uas muaj ntawv tso cai siv kev noj zaub mov zoo thiab kev ua haujlwm puas hlwb hauv kuv txoj haujlwm nrog cov neeg siv khoom. Ntau tus ntawm lawv raug kev txom nyem los ntawm kev paub txog cov tsos mob, nrog thiab tsis paub tias yog kev puas siab puas ntsws, nyob rau ntau lub hnub nyoog.

Lub Network Hypothesis ntawm Alzheimer's Disease

Qhov kev xav no muaj qee cov pov thawj zoo los txhawb nws thiab siv cov ntaub ntawv los ntawm kev ua haujlwm MRI. Qhov lawv pom yog tias muaj teeb meem nyob rau hauv qhov sib txawv ntawm lub hlwb hais lus rau ib leeg thiab nws tshwm sim thaum ntxov ntawm tus kab mob. Qhov tseeb, cov neeg uas muaj qhov ua rau muaj tus kab mob Alzheimer's (piv txwv li, APOE-ε4 cov neeg nqa khoom) tuaj yeem pib pom qhov kev sib txuas tsis zoo tshwm sim ua ntej cov tsos mob. Nws zoo li pib nyob rau hauv lub posterior default mode network (DMN), thiab thaum nws pib taug kev mus rau dorsal mloog network (DAN), cov kws tshawb fawb pib pom cov tsos mob tshwm sim ntawm kev puas hlwb me me (MCI). Qhov no ntawm lub hlwb ua raws li nws lub npe qhia. Nws tso cai rau koj ua tib zoo mloog. Yog tias koj tsis tuaj yeem mloog zoo, koj tsis tuaj yeem khaws cov ntaub ntawv zoo, thiab lub cim xeeb episodic yuav ua rau tsis zoo.

ep·i·sod·ic mem·ory - noun (Oxford Languages ​​via Google) ib hom kev nco mus sij hawm ntev uas muaj kev nco qab txog cov kev paub dhau los ua ke nrog lawv cov ntsiab lus ntawm lub sijhawm, qhov chaw, kev xav, thiab lwm yam.
"Cov txiaj ntsig tau qhia tias cov neeg koom siv tau siv lub cim xeeb rov qab los ntawm cov lus hais hauv txhua qhov xwm txheej"

nco nco txog qhov kev paub dhau los.
"lub hippocampus yog qhov tseem ceeb hauv kev tsim cov cim xeeb" 

Raws li cov kws tshawb fawb saib qhov txo qis hauv kev sib txuas ua haujlwm tau zoo, lawv tuaj yeem soj ntsuam thiab txawm tias kwv yees qhov kev ua haujlwm tsis zoo hauv cov haujlwm tseem ceeb uas suav nrog kev ceeb toom, taw qhia rau qhov xav tau lawv qhov xav tau, thiab tuav tes. Kuj tseem muaj kev ua haujlwm tsis zoo hauv kev sib txuas hauv kev sib txuas lus, uas suav nrog cov txheej txheem tseem ceeb ntawm lub hlwb ntawm lub anterior cingulate thiab ventral anterior insular cortices, uas kuj suav nrog cov nodes tseem ceeb ntawm kev sib txuas lus hauv amygdala, ventral striatum, brainstem, thalamus, thiab hypothalamus. Cov neeg sib txawv yuav ntsib teeb meem kev sib txuas hauv ntau qhov chaw ntawm lub paj hlwb, thiab yog li koj tuaj yeem pom muaj teeb meem nrog tus neeg lub peev xwm los ntsuas lawv tus kheej kev ua haujlwm lossis kev cuam tshuam ntawm kev pom thaum muaj kab mob txuas ntxiv mus.

Tsis txaus hlwb zog

Yog tias koj muaj cov tsos mob ntawm neurodegenerative disorder (pob hlwb pos, MCI, dementia), koj muaj cov piam thaj hauv lub zog metabolism hauv koj lub hlwb. Qhov ntawd txhais li cas? Nws txhais tau tias muaj qee qhov ntawm koj lub hlwb uas noj cov piam thaj tsawg dua thiab ua kom lub zog tsawg dua. Thiab nws tau tshwm sim feem ntau nyob rau hauv koj thaj chaw nruab nrab ntawm lub cev nqaij daim tawv uas muaj xws li hippocampus, entorhinal cortex, thiab posterior cingulate cortex peb nyuam qhuav tham, uas yog ib feem ntawm posterior DMN. Qhov no yog qhov teeb meem vim tias cov no yog thaj chaw uas cov kws tshawb fawb paub tias muaj feem cuam tshuam thaum lub cim xeeb episodic ua tsis taus. Tab sis qhov txo qis ntawm cov roj hauv cov ntu ntawm lub paj hlwb yog hais txog ntau tshaj li kev nco ua haujlwm xwb. Nws yog ib qho tseem ceeb kom nkag siab tias lub hlwb siv lub zog loj heev los kho cov neurons, thiab thaum muaj kev tsis txaus ntawm lub zog, koj lub hlwb hlwb tsis tuaj yeem ua cov haujlwm tseem ceeb los xyuas kom muaj kev noj qab haus huv thiab kev ua haujlwm ntawm cov hlwb:

• kho cov membranes
• tsim thiab ua haujlwm ntawm cov roj teeb ntawm tes (mitochondria)
• khaws cov as-ham uas xav tau los tsim cov neurotransmitters thiab enzymes
• muaj zoo zog pulses ntawm kev ua muaj peev xwm mus teeb liab ntawm neurons

Kuv tuaj yeem mus thiab txog txhua txoj hauv kev tsuas yog tsis muaj lub zog txaus hauv lub hlwb tsim muaj cov kab mob neurodegenerative cascade uas yog qhov sib npaug ntawm lub tsheb ciav hlau khiav tawm ntawm kev paub txog kev puas tsuaj.

Tam sim no, txaus ntawm no tham txog dab tsi mus tsis ncaj ncees lawm. Cia peb pib sib tham txog yuav ua li cas kho nws.

Nkag mus rau Ketones

Ketones muab lwm yam roj rau thaj chaw ntawm lub paj hlwb uas muaj zog tshaib plab. Nco ntsoov peb cov kev sib tham txog qee qhov chaw ntawm lub hlwb tsis tuaj yeem siv cov piam thaj rau roj thiab? Ketones bypass cov faulty mechanisms thiab upregulates lub zog metabolism. Ketones yog qhov taw qhia cov molecules, thiab muaj ntau lwm yam haujlwm zoo dua li lwm yam roj.  

Ketogenic kev cuam tshuam tam sim no yog ib qho kev cog lus neurotherapeutic lub tswv yim los kho cov kev txawj ntse hauv MCI thiab AD

Roy, M., Edde, M., Fortier, M., Croteau, E., Castellano, CA, St-Pierre, V., … & Descoteaux, M. (2022). Kev cuam tshuam ketogenic txhim kho dorsal mloog network kev ua haujlwm thiab kev sib txuas ntawm cov qauv hauv cov kev paub tsis meej me ntsis. Neurobiology ntawm Kev Laus. https://doi.org/10.1016/j.neurobiolaging.2022.04.005

Cov txiaj ntsig zoo tshaj plaws ketones muab yog roj rau cov chaw tshaib plab ntawm lub hlwb. Tab sis lawv ua ntau yam ntxiv. Ketones yog qhov tseem ceeb rau kev kho lub hlwb thiab kho. Piv txwv li, lawv tab tom tsim cov blocks rau myelin sheaths uas tiv thaiv cov hlab ntsha los ntawm hluav taws xob tua hluav taws xob ntawm qhov muaj peev xwm ua tau zoo thiab xav tau kev kho tas li. Nyob rau hauv lawv lub luag hauj lwm raws li cov cim qhia lub cev, lawv tig rau txoj kev tiv thaiv kab mob, txawm hais tias kuv yuav sib cav hais tias yog kev cia siab rau exogenous ketone tshuaj ib leeg yam tsis tau hloov cov khoom noj inflammatory, cov txiaj ntsig no yuav tsis pom zoo rau tus neeg ua haujlwm kho lawv lub hlwb. Ketones txo oxidative kev nyuaj siab thiab txhim kho kev sib txuas ntawm lub hlwb cov qauv, txawm nyob rau hauv lub sib sib zog nqus teeb teeb meem nyob rau hauv lub hlwb. Lawv txhawb kev tsim cov hlwb-Derived Neurotrophic Factor (BDNF), uas ua rau muaj kev sib txuas zoo dua thiab kho neuronal, thiab cov tshuaj no ua lub luag haujlwm zoo hauv kev nco thiab hippocampus.

Ketones kuj tseem txhim kho kev ncaj ncees ntawm cov ntshav-hlwb lub hlwb, uas muaj txoj haujlwm tseem ceeb ntawm kev tiv thaiv lub hlwb los ntawm co toxins lossis lwm yam tshuaj uas yuav ua rau cov txheej txheem inflammatory uas tuaj yeem ua rau muaj kev puas tsuaj rau lub hlwb. Lawv upregulate zus tau tej cov glutathione, uas yog lub cev tus kheej antioxidant system tsim los pab tiv thaiv oxidative kev nyuaj siab (yog, tshwj xeeb tshaj yog nyob rau hauv lub hlwb).

Ketones muab ntau theem kev cuam tshuam tsis yog tsuas yog cawm kev paub tab tab sis kho lub hlwb thiab qeeb lossis txawm tias nres, cov txheej txheem neurodegenerative.

Kev Kho Mob Ketogenic

Thaum koj ua koj qhov kev tshawb fawb txog kev txhim kho kev txawj ntse, koj yuav ntsib kev tshawb fawb txog ketones thiab ntau txoj hauv kev uas ketones tuaj yeem muab tau. Muaj cov ketones exogenous uas ib tus neeg tuaj yeem haus lossis ntxiv rau cov zaub mov hauv daim ntawv ntawm MCT roj, piv txwv li. Los yog muaj cov ketones uas yog tsim los ntawm ib tug neeg uas zom cov rog rog los yog lawv lub cev rog rau hauv ketone lub cev. Thiab muaj, ntawm chav kawm, kev sib xyaw ntawm ob. Cov kev tshawb fawb feem ntau yog saib MCT roj. MCT roj yog roj zoo heev rau lub hlwb, thiab kuv xav kom nws. Tab sis nws tuaj yeem ua rau mob plab zom mov ntau, yog li nws yuav tsum tau ua haujlwm hauv cov koob tshuaj maj mam. Txawm li cas los xij, vim tias nws muaj qhov tsis zoo digestive (mob plab) rau ntau tus neeg, nws tuaj yeem nyuaj lossis qee zaum txawm tias tsis tuaj yeem ua haujlwm txog li ib koob tshuaj uas txo cov tsos mob.

Los ntawm qhov kev pom zoo xwb, yog tias koj hais kom leej twg noj cov roj MCT, lawv yuav qhia koj txawm tias ib tablespoon (15mL) tuaj yeem ua teeb meem. Hauv ib txoj kev tshawb fawb, kuv tau saib cov neeg koom nrog uas yuav tsum pib nrog 50mL (txog 3 TBSP) thiab ua haujlwm txog li 250mL (kwv yees li 17 TBSP). Cov neeg tuaj koom yuav tsum tau ua haujlwm txog qhov koob tshuaj loj li 6 lub hlis, thiab cov ntaub ntawv pov thawj ua ntej ntawm txoj kev tshawb no (thaum lub sijhawm kuv tau sau cov ntawv blog no) tsis tau qhia meej tias cov neeg koom yuav xav tau koob tshuaj rau lawv tus kheej li cas. (Saib Roy, thiab al., 2022 nyob rau hauv cov ntaub ntawv).

Vim li cas tsuas yog noj MCT roj ntau tsis yog lus teb

Koj lub xeev ntawm insulin tsis kam kuj tseem ceeb hauv kev mob neurodegenerative. Nws yog qhov zoo rau kev nce koj lub hlwb roj nrog MCT roj, uas yuav pab muab ketones ua txhua yam uas kho koj lub hlwb. Tab sis tsom mus rau tsuas yog nce ketones tsis tau hais txog qhov tseeb tias lub hlwb ntxuav hauv qabzib tsis yog lub hlwb zoo siab. Yog tias koj tau tsim cov tshuaj insulin, koj yuav tsum tau hloov koj cov zaub mov kom zoo txhawm rau txhim kho lossis thim rov qab cov kab mob no.

Tshwj xeeb, thaum cov tib neeg uas muaj ntshav qab zib ntau ntxiv tseem tsis tau pom qhov kev paub tsis zoo, lawv tau muaj qhov atrophy hauv cheeb tsam hauv hippocampus thiab inferior parietal cortex, thiab nce amyloid tsub zuj zuj hauv precuneus cortex.

Honea, RA, John, CS, Green, ZD, Kueck, PJ, Taylor, MK, Lepping, RJ, … & Morris, JK (2022). Kev sib raug zoo ntawm yoo mov qabzib thiab longitudinal Alzheimer's kab mob imaging markers. Alzheimer's & Dementia: Kev Tshawb Fawb Kev Tshawb Fawb & Kev Pabcuam Chaw Kho Mob, 8(1), e12239. https://doi.org/10.1002/trc2.12239

Tsis tas li ntawd, thaum koj muaj hnub nyoog, qhov tshwm sim uas koj tau tsim cov tshuaj insulin nce ntxiv, thiab kev txhim kho koj cov insulin rhiab heev tuaj yeem pab tiv thaiv kab mob ntawm kev laus. Cov neeg uas muaj cov tshuaj insulin ntau dua yog qhov kev pheej hmoo siab ntawm ntau cov txheej txheem kab mob, ncaj qha rau hauv qhov ua rau muaj kev cuam tshuam los yog, tsawg kawg, hauv kev sib koom siab thiab xav tsis thoob. Dab tsi yog qee yam ntawm cov kab mob pom tias muaj cov hauv paus hauv kev kho tsis tau cov tshuaj insulin? Los yog, tsawg kawg, kev koom tes siab heev? Lawv suav nrog cov hauv qab no:

• Mob plawv - Mob ntshav siab, Atherosclerosis, Cardiomyopathy, Hyperlipidemia profiles
• Neurological - Alzheimer's Disease, Parkinson's Disease, Vascular Dementia, Migraine Headaches, Neuropathy
• Mob Cancer - Lub mis, Prostate, thiab Colorectal
• Musculoskeletal - Sarcopenia, Osteoporosis, Osteoarthritis
• Digestive - Gout, Reflux Esophagitis (GERD), teeb meem dhau cov quav (Gastroparesis)
• Kab mob siab - Hyperlipidemia (qhia txog qhov teeb meem nrog lub siab, tsis yog lub plawv plawv),
• Kab mob raum thiab raum - Gallstones, raum pob zeb, raum tsis ua haujlwm

Cov txheej txheem kab mob no yuav nyiag koj qhov tseem ceeb thiab lub neej zoo ib yam nkaus li cov tsos mob tsis paub kho thiab Alzheimer's kab mob lossis lwm yam dementia yuav. Tab sis dua li qhov tseeb, cov txheej txheem kab mob no tseem cuam tshuam rau koj lub hlwb tsis ncaj.

Tsuas yog muab lub paj hlwb nrog lwm qhov chaw siv roj tsis yog qhov kev cuam tshuam txaus rau kev puas siab puas ntsws me me lossis kab mob Alzheimer thaum ntxov. Tsis yog peb mob siab rau tag nrho lub cev thiab koj lub neej yav tom ntej. Piv txwv li, yog tias koj muab koj tus kheej ntau cov roj MCT, thiab zoo dua hauv koj lub hlwb, tab sis tsis txhob hloov koj cov zaub mov los pab rov qab insulin tsis kam (uas noj cov zaub mov ketogenic ua), ces thaum koj atherosclerosis loj tuaj, koj yuav pib muaj kab mob plawv. .

Raws li koj cov kab mob plawv loj zuj zus tuaj, koj yuav pib muaj teeb meem nrog cov pa oxygen thiab cov as-ham raug tso rau hauv koj lub hlwb thiab koj lub cev. Thiab qhov ntawd tsuas yog ib qho ntawm ntau lub tswv yim uas ua rau tsis zoo hauv cov kab mob plawv uas tuaj yeem cuam tshuam rau kev noj qab haus huv ntawm lub hlwb. Lub plawv tsis ua haujlwm yuav cuam tshuam rau koj lub hlwb. Kuv tsis mob siab npaum li cas MCT roj koj noj.

xaus

Kuv pom cov txiaj ntsig kho mob zoo dua qub thaum peb siv cov khoom noj ketogenic rau kev kho mob ntawm kev puas hlwb, txawm tias nws yog me ntsis hnyav dua-ntawm-lub-mill hlwb pos huab uas ntau tus neeg tau ntsib, kuaj pom Mild Cognitive Impairment (MCI), lossis txawm. thaum ntxov dementia. MCT roj thiab lwm cov tshuaj ketone exogenous yog siv los tsim raws li lub hauv paus ketogenic ntawm lub hlwb roj uas tshwm sim nrog kev kho cov carbohydrate txwv. MCT roj yog ib qho kev txhim kho. Nws tsis yog qhov kev cuam tshuam uas txuag koj lub hlwb. MCT roj los ntawm nws tus kheej yog ib qho kev sim band-pab rau cov txheej txheem neurodegenerative. Yog tias tsis muaj qhov txo qis hauv cov carbohydrates uas kho hyperglycemia thiab insulin tsis kam, koj tsis tuaj yeem hais txog cov txheej txheem neurodegenerative uas yuav tshwm sim hauv keeb kwm yav dhau. Txawm hais tias cov no tau tshwm sim ncaj qha rau hauv lub hlwb (uas kuv lav tias lawv yog) lossis los ntawm cov txheej txheem kab mob sib kis, xws li cov uas peb twb tau nyeem txog.

Kuv tsis qhia koj txog qhov tsis txaus ntawm MCT roj hauv kev kho cov txheej txheem neurodegenerative ua rau koj poob siab. Kuv paub qhov muaj peev xwm hloov tau koj cov zaub mov kom qeeb, nres lossis txawm rov qab koj cov txheej txheem kab mob nyuaj, thiab koj yuav tsis paub tseeb tias qhov ntawd yuav zoo li cas. Koj tuaj yeem pom cov ntawv blog no pab tau.

Keto noj cov cai rau kev puas hlwb

Keto ntawm pob nyiaj siv rau kev puas hlwb

Kuv sau qhov no vim yog koj lossis ib tus neeg koj hlub raug mob los ntawm kev paub txog cov tsos mob, kuv tsis xav kom koj txhaj tshuaj MCT roj, tsis pom kev txhim kho, thiab tom qab ntawd tso tseg kev ntseeg tias ketones tuaj yeem pab koj. MCT roj ib leeg tsis yog tib theem ntawm kev cuam tshuam uas kev noj zaub mov zoo ketogenic yog, thiab nws tsis yog tib qho kev cuam tshuam koj xav tau yog tias koj ua ke ob. Kuv tau muaj ntau tus neeg siv uas xav tias tsis muaj qhov sib txawv thaum ntxiv MCT roj tab sis xav tias lawv lub hlwb kho thiab txhim kho kev ua haujlwm siv cov khoom noj ketogenic.

Yog li yog tias MCT roj tsis txo koj cov tsos mob, thov tsis txhob tso kev cia siab.

Muab cov ketones, txawm tias los ntawm kev noj zaub mov zoo ketogenic lossis nrog nce MCT noj, yog thawj kauj ruam hauv kev cawm txoj kev paub. Cov kauj ruam thib ob tuaj yeem yog kev tshuaj xyuas nutrigenomic kom ntseeg tau tias kev noj micronutrient txaus thiab kev kuaj ntxiv los txiav txim siab lwm yam hauv cov txheej txheem kab mob, feem ntau ua nrog kev kuaj tshuaj. Tab sis ua ntej tshaj plaws, peb yuav tsum cawm lub hlwb lub zog.

Ketones ua li ntawd.

Tab sis txawm koj txiav txim siab, tsis txhob nkim sijhawm. Lub sijhawm yog qhov tseem ceeb hauv kev kho mob neurodegenerative mob.

Yog tias koj raug kev txom nyem los ntawm kev paub txog cov tsos mob ntawm lub hlwb pos huab, nyuaj rau kev tsom lossis nco txog tej yam, lossis kev saib xyuas, thiab teeb meem nrog lub siab koj yuav xav kawm ntxiv txog kuv qhov kev pab cuam online.

Brain Fog Recovery Program

Yog tias koj xav sau npe rau daim ntawv xa mus kawm txog cov kev kawm yav tom ntej, cov chav kawm, thiab kev kawm, koj tuaj yeem ua li no:

Vim koj muaj cai paub txhua txoj kev uas koj tuaj yeem hnov ​​​​zoo dua.

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