Yuav ua li cas noj cov zaub mov ketogenic pab kho lub hlwb xau thiab ua rau cov ntshav-hlwb barrier muaj zog thiab muaj zog dua?
Kwv yees li ntawm lub sijhawm nyeem ntawv: 17 feeb
Qhov ntawd yog ib lo lus nug zoo heev. Yog li kuv yuav teb nws. Hauv tsab ntawv blog no, peb yuav los sib tham txog dab tsi cov ntshav-hlwb barrier yog dab tsi, cov tsos mob dab tsi peb tuaj yeem xav tias yuav tshwm sim yog tias nws puas thiab xau, thiab txawm tias cov kev kuaj sim uas tuaj yeem siv los sim ntsuas yog tias nws leaky.
Koj cov ntshav-hlwb barrier (BBB) tseem ceeb heev.
Ua ntej, tsuas yog me ntsis ntawm lub cev thiab kev ua haujlwm. Tsuas yog txaus kom koj nkag siab txog dab tsi cuam tshuam.
BBB cais cov ntshav los ntawm cov kua cerebrospinal extracellular thiab tiv thaiv lub hlwb los ntawm cov kab mob hauv cov ntshav thiab cov co toxins thaum tso cai rau kev nthuav tawm ntawm oxygen, carbon dioxide, thiab me me lipophilic molecules / ethanol. Kev saib xyuas ntawm BBB yog qhov tseem ceeb rau kev tswj xyuas nruj ntawm cov tshuaj muaj pes tsawg leeg ntawm lub paj hlwb interstitial kua (ISF) qhov tseem ceeb rau kev ua haujlwm ntawm synaptic thiab muab ib daim ntawv tiv thaiv cov kab mob hauv cov ntshav.
Kakaroubas, N., Brennan, S., Keon, M., & Saksena, NK (2019). Pathomechanisms ntawm ntshav-hlwb teeb meem cuam tshuam hauv ALS. Phau ntawv Journal Neuroscience, 2019. https://doi.org/10.1155/2019/2537698
BBB yog ib qho kev sib sau ntawm cov hlab ntsha thiab astrocytes uas ua ke kom cov khoom tawm ntawm lub hlwb los ntawm cov kab mob hauv lub cev. Nws muaj cov neeg thauj khoom sib txawv uas tso cai rau qee yam hla dhau.
Tab sis ib yam li lub plab khoob vim BBB poob qis hauv kev noj qab haus huv nws tsis tuaj yeem tswj hwm nws txoj kev ncaj ncees thiab txhua yam nkag mus rau hauv lub hlwb uas yuav tsum tsis txhob ua. Cov no yuav suav nrog:
- Tshuaj thiab Environmental Toxins
- Cov kab mob (cov kab mob thiab kab mob)
- Cov zaub mov muaj protein ntau (piv txwv li, gluten)
- Ntau yam inflammatory mediators hauv cov hlab ntsha (xws li lipopolysaccharide)
- Circulating anti-lub cev
- Hormone imbalances (qhov tseeb hypothyroidism)
Thaum cov khoom no tau los ntawm cov hlab ntshav-hlwb thaiv lawv qhib lub hlwb lub cev tiv thaiv kab mob los sim tiv thaiv lub hlwb. Tshwj xeeb, microglial hlwb ua kom qhib tau. Yog tias koj muaj BBB leaky, nws txhais tau tias txhua yam tau nce mus rau txhua lub sijhawm uas tsis yog. Thiab qhov no txhais tau tias kev ua kom microglial tshwm sim tas li. Qhov ntawd tsis zoo. Qhov ntawd teeb tsa theem rau mob neuroinflamation. Thiab yog tias koj lub hlwb tsis tuaj yeem kho nws tus kheej sai txaus kom ua raws li kev puas tsuaj los ntawm kev mob neuroinflamation, nws yuav teeb tsa koj rau cov txheej txheem neurodegenerative.
Lub hlwb xav tau micronutrients los kho qhov kev puas tsuaj, ua rau cov neurotransmitters thiab cov enzymes tseem ceeb, thiab tsim kom muaj zog. Koj puas paub tias koj lub hlwb tau txais cov vitamins feem ntau nws xav tau li cas rau cov txheej txheem no? Koj BBB. Yog, yog lawm! Feem ntau ntawm cov vitamins tseem ceeb hauv dej-soluble (piv txwv li, B vitamins) thiab lwm yam tseem ceeb metabolites raug thauj mus rau hauv lub hlwb siv cov thauj tshwj xeeb hauv BBB.
Qee qhov kev thauj mus los no yog siv los hla cov piam thaj mus rau hauv lub hlwb. Raws li peb tau tham hauv cov lus dhau los, qhov no tsis tas yuav yog cov piam thaj uas koj noj. Koj lub cev zoo siab dua los ua cov piam thaj hauv qab koj xav tau rau qee qhov ntawm koj lub hlwb ua haujlwm. Tab sis yog tias koj BBB puas lawm thiab cov khoom siv thauj khoom siv rau lub hom phiaj ntawd puas lossis tsis ua haujlwm (BBB tuaj yeem dhau los ua insulin resistant) ces koj yuav tsis tau siv cov piam thaj rau lub zog. Thiab nyob rau hauv txoj kev no, BBB deterioration tuaj yeem tshwm sim thiab nws qhov kev puas tsuaj tuaj yeem ua rau muaj kev kub ntxhov hauv lub hlwb.
Yog tias koj BBB puas lawm, qhov ntawd tuaj yeem ua teeb meem rau tag nrho cov neeg thauj khoom, uas nws txoj haujlwm yog kom tau txais cov as-ham thiab roj rau hauv koj lub hlwb.
Qhov no txhais tau tias koj lub hlwb muaj hnub nyoog ntau dua li qhov nws xav tau. Thiab nws tsis muaj teeb meem yog tias koj yog 15 lossis 27 lossis 34 lossis hauv koj 40s lossis 50s lossis 60s. Cov txheej txheem neurodegenerative tshwm sim txhua lub hnub nyoog. Ib tug leaky BBB tsis yog ib tug neeg laus qhov teeb meem. Nws yog "txhua tus neeg ntawm txhua lub hnub nyoog teeb meem." Thiab nws yuav tsum tau txiav txim siab thiab hais txog.
Tsis txhob ua rau kuv yuam kev. Kuv zoo siab tau pom leaky GUT tau txais huab cua ntau thiab kev txhawj xeeb. Kuv cia siab tias nws yog thaum kawg ntawm tib neeg lub radars ntawm txoj kev tiag. Kev kho lub plab khoob yog qhov tseem ceeb vim tias koj yuav tsum ua kom lub cev tiv thaiv kab mob nyob ntsiag to kom lub hlwb tiv thaiv kab mob tsis ua haujlwm dhau. Koj xav tau cov plab zom mov noj qab haus huv kom muaj peev xwm zom tau thiab nqus tau koj cov as-ham los ntawm koj lub plab thiab koj xav tau microbiome noj qab haus huv rau tej zaum ntau txhiab tus laj thawj.
Koj tuaj yeem kawm paub ntau ntxiv txog kev noj qab haus huv microbiomes no.
Tab sis muaj tag nrho lwm qhov teeb meem uas yuav tsum tau txhawb nqa thiab nkag siab los ntawm cov pej xeem thiab cov neeg uas tawm tsam lub hlwb uas tsis ua haujlwm zoo li lawv xav tau. Thiab yog vim li cas cov ncej no tau raug sau. Lub hlwb tawg yog ib yam.
Thaum BBB tawg lawm qhov tseem ceeb uas tshwm sim yog tias koj tau txais neuroinflamation. Thaum muaj cov txheej txheem neuroinflammatory, tib neeg pib yws txog cov tsos mob ntawm lub hlwb pos huab.
Thaum koj muaj lub hlwb pos huab, nws txhais tau tias ib yam dab tsi cuam tshuam nrog kev ua haujlwm synapse.
Synapses yog ib qho tshwj xeeb thiab tseem ceeb ntawm cov hlwb neuronal. Lawv yog cov chaw tseem ceeb ntawm kev sib txuas lus ntawm cov hlwb neuronal, thiab yog li ntawd, lawv koom nrog txhua yam ntawm neuronal physiology. Kev ua haujlwm synaptic kom zoo yog qhov yuav tsum tau ua ua ntej rau kev ua haujlwm ntawm lub hlwb, thiab txawm tias muaj kev cuam tshuam me me tuaj yeem ua rau muaj kev puas hlwb.
Xylaki, M., Atzler, B., & Outeiro, TF (2019). Epigenetics ntawm Synapse hauv Neurodegeneration. Tam sim no neurology thiab neuroscience qhia, 19(10), 1-10. https://doi.org/10.1007/s11910-019-0995-y
Neuroinflammation cuam tshuam nrog cov hlab ntsha conduction ceev thiab koj yuav pom tias kev xav thiab lub cev muaj zog ua haujlwm tsis zoo lossis tuaj yeem yooj yim dua. Neuroinflammation kuj "uncouples" mitochondria. Mitochondria yog koj lub cell powerhouses. Lawv muab lub zog koj lub cell xav tau ua haujlwm. Los ntawm firing cov synapses kom lub cell noj qab haus huv nrog lub zog los ua lub hauv paus ntawm lub cell tsev tu. Yuav ua li cas uncoupled mitochondria xav li cas? Nws zoo li lub hlwb qaug zog. Koj lub hlwb tau nkees sai. Tej zaum koj tsis tuaj yeem tsav tsheb hnyav ntxiv, tiv thaiv kev sib raug zoo ntev lossis nyeem ntau npaum li koj tau siv. Koj lub peev xwm los ua cov haujlwm thiab ua tib zoo mloog yog txo qis.
Neuroinflammation tuaj yeem wax thiab ploj mus. Qee lub lis piam muaj kev xav thiab kev xav tsis zoo, thiab lwm lub lis piam koj yuav pom cov tsos mob tsawg dua. Qhov no tsuas yog txhais tau hais tias lub hlwb tau muaj kev vam meej, qee lub sijhawm, tswj cov txheej txheem inflammatory thiab kho cov neurodegeneration raws li nws tshwm sim.
Tab sis raws li koj tuaj yeem xav, cov hauv paus ntsiab lus uas tsim kom muaj cov kuab paug BBB yuav tsum tsis txhob raug ignored, thiab nyob rau qee lub sij hawm lub paj hlwb pos yuav ua rau mob, vim hais tias lub cev tsis muaj zog yuav ua rau overactive thiab tus nqi ntawm kev puas tsuaj yog ua tiav outstrips lub cev antioxidant systems. , tsim oxidative kev nyuaj siab thiab teeb tawm cov txheej txheem tseem ceeb neurodegenerative.
Cov pov thawj loj hlob qhia tau hais tias oxidative stress (OS) ua lub luag haujlwm tseem ceeb hauv kev hloov pauv BBB.
Kadry, H., Noorani, B., Bickel, U., Abbruscato, TJ, & Cucullo, L. (2021). Kev sib piv kev ntsuas ntawm hauv vitro BBB nruj kev sib tshuam kev ncaj ncees tom qab raug cov pa luam yeeb thiab e-luam yeeb vapor: Kev ntsuam xyuas ntau ntawm kev tiv thaiv ntawm metformin siv cov cim me me-molecular-qhov hnyav paracellular. Cov kua dej thiab cov teeb meem ntawm CNS, 18(1), 1-15. https://doi.org/10.1186/s12987-021-00261-4
Kuv pheej hais txog cov txheej txheem neurodegenerative "cov txheej txheem" vim hais tias thaum qee zaus neurodegeneration tshwm sim, thaum nws nce mus rau hauv ib yam dab tsi ntev (aka txheej txheem) cov neurodegeneration pub nws tus kheej, tsim lub voj ntawm kev puas tsuaj tas li, kev noj zaub mov tsis zoo, ntxiv neuroinflammation, thiab lwm yam uas tuaj yeem ua rau nws. nyuaj dua los tig nws ib ncig tom qab ib qho kev puas tsuaj. Yog tias tso cai mus tsis tau tshuaj xyuas nws tuaj yeem ua rau muaj kev puas tsuaj uas tsis tuaj yeem kho. Thiab yog vim li cas qhov blog no suab lub tswb ceeb toom tias lub hlwb pos yuav tsum tau ua tiag tiag thiab kho nrog kev noj haus muaj zog thiab kev kho mob hlwb uas cuam tshuam cov hauv paus hauv paus ntawm cov txheej txheem neurodegenerative. Txawm yog vim li cas los yog kev kuaj mob.
Kuv yuav ua li cas thiaj paub yog tias kuv muaj lub hlwb tawg?
Muaj cov cim tshuaj tiv thaiv sib txawv cuam tshuam nrog BBB permeability. Cov no suav nrog S100B, aquaporin 4, glial fibrillary acidic protein, thiab zonulin antibodies. Koj tus kws kho mob ua haujlwm tuaj yeem xaj cov kev sim zoo li no los ntawm Cyrus Laboratory.
Koj tuaj yeem kuaj tau, tab sis ntawm no yog qhov khoom. Yog tias koj paub tias koj muaj lub plab khoob, lossis koj tau kuaj pom tias muaj lub plab xau, ces muaj qhov zoo heev uas koj muaj BBB leaky. Vim tias lub plab khoob tso cai rau cov khoom nkag mus rau hauv cov hlab ntsha uas yuav tsum tsis txhob ua. Thiab qee yam ntawm cov no yog kev tawm tsam ncaj qha rau BBB. Qhov kev sib raug zoo ntawm lub plab hnyuv thiab leaky BBB yog super siab. Lawv mus ua ke.
Piv txwv li, cov tshuaj tiv thaiv ua rau gluten, uas tsis nres los ntawm BBB tuaj yeem khi rau astrocytes thiab neurofilament proteins hauv cerebellum thiab ua rau muaj mob hu ua Gluten Ataxia. Cov txheej txheem neurodegenerative ua rau qhov kev kuaj mob no tuaj yeem zoo li lub paj hlwb cov tsos mob uas muaj xws li teeb meem hais lus, khib tingling rhiab heev nyob rau hauv lub extremities, tsis zoo sib koom tes thiab sib npaug, thiab tej zaum muaj teeb meem siv koj txhais tes thiab ob txhais ceg los yog koj cov ntiv tes thiab tes (xws li, koj pib mus. pom muaj teeb meem ntxiv kom koj cov ntiv tes ua haujlwm thaum koj crochet).
Tej zaum koj muaj cov co toxins hauv koj lub cev, txawm tias dhau los ntawm kev raug tshuaj los ntawm cov khoom siv hauv tsev lossis qee yam koj nqus tau los ntawm koj ib puag ncig taug kev hauv txoj kev (qhov no tshwm sim tas li). Yog tias koj BBB noj qab nyob zoo, cov no yuav tsis hla mus rau hauv lub hlwb. Tab sis yog tias nws tsis noj qab haus huv, txawm tias cov tshuaj twg nws yuav hla mus rau hauv lub hlwb, ua kom microglia uas tso cov cytokines inflammatory.
Cov khoom tsis zoo no uas ua los ntawm koj lub BBB, thiab yuav tsum tsis txhob nyob ze ntawm lub hlwb, yuav khi thiab txuas rau cov protein sib txawv thiab ua rau cov khoom tawg. Kuv txhais li cas los ntawm "tawg khoom" raws nraim? Kuv txhais tau tias lawv yuav khi rau lwm qhov chaw yuav tsum khi rau, thiab tsis tso cai rau ib yam dab tsi ua haujlwm zoo. Lawv yuav nkag mus rau hauv txoj kev thiab inhibit cov txheej txheem tseem ceeb uas koj lub hlwb xav tau ua haujlwm thiab ua kom koj lub hlwb noj qab nyob zoo.
Yuav ua li cas koj BBB tau leaky
Koj BBB yog qhov pib ntawm cov hlwb endothelial thiab astrocytes (astroglia). Ob leeg ntawm no tau yooj yim puas nyob rau hauv ib puag ncig ntawm mob o. Cov kab mob ntev uas ua rau muaj mob hauv lub cev (uas yog txhua tus ntawm lawv) tuaj yeem ua lub luag haujlwm hauv kev rhuav tshem BBB. Qee cov tshuaj uas cov tshuaj tseem ceeb siv los kho cov kab mob ntev tuaj yeem ua rau muaj kev puas tsuaj ntawm BBB (xws li corticosteroids). Nws kuj tseem tuaj yeem tshwm sim los ntawm kev raug mob ntawm lub hlwb (TBI) (xws li, tsheb sib tsoo, ntog) vim tias BBB yuav kho tsis tau txaus tom qab muaj kev tsim txom. Cov teeb meem mob plab inflammatory tuaj yeem tsim lub xeev ntawm cov kab mob hauv lub cev vim tias cov plab hnyuv (permeability) tso tawm ntau zonulin lossis lipopolysaccharides (LPS) mus rau hauv cov hlab ntsha, uas tom qab ntawd cuam tshuam kev noj qab haus huv ntawm BBB ncaj qha.
Dab tsi ntxiv ua teeb meem rau kuv BBB?
Yog tias koj muaj qib siab ntawm homocysteine ntawm koj qhov kev kuaj ntshav, koj muaj feem ntau dua tias koj qhov BBB tau xau. Yog tias koj muaj genetic SNPs xws li MTHFR, koj muaj kev pheej hmoo siab ntawm cov teeb meem ua kom koj BBB kom zoo thiab noj qab nyob zoo. Koj tuaj yeem txhim kho qhov tsis sib xws los ntawm kev noj cov tshuaj methylated B-complex.
Lwm yam uas tsim BBB permeability muaj xws li cov hauv qab no:
- Sedentary lub neej
- Kev haus cawv
- Mob pw tsaug zog deprivation
Tej zaum koj yuav xav paub seb yuav ua li cas thiaj kho tau.
Yuav ua li cas cov zaub mov ketogenic tuaj yeem pab kho lub hlwb tawg
Feem ntau ntawm peb cov ntaub ntawv hais txog yuav ua li cas ketones cuam tshuam rau BBB los ntawm kev tshawb fawb tsiaj. Tus kheej, kuv zoo siab los ntawm qhov ntawd. Kuv tsis xav kom leej twg txiav rau hauv leej twg lub taub hau sim kom paub seb dab tsi tshwm sim nyob rau ntawd. Yog li tsis txhob poob rau lub tswv yim tias vim tias cov no los ntawm cov tsiaj tshawb fawb qee qhov kev tshawb pom tsis raug cai rau koj BBB. Muaj ntau lub tshuab tib yam mus.
Txhim kho lub hlwb thiab BBB metabolism
Thaum koj lub cev ua ketones ntawm cov khoom noj ketogenic, nws tuaj yeem muab lwm lub zog rau BBB puas. Lawv tsuas yog tshwm sim los yog qhov nyiam siv roj rau lub hlwb. Lawv nkag mus rau hauv lub hlwb yam tsis muaj fuss los yog muss xav tau ib tug zoo siab los yog ua hauj lwm thauj (xws li, yooj yim diffusion los yog yooj yim diffusion). Monocarboxylate transporters mediate ketone lub cev nkag mus rau hauv lub hlwb, thiab lawv muaj ntau dhau los ntawm BBB, suav nrog cov plasma membrane ntawm choroid plexus, endothelial thiab epithelial hlwb, glia, thiab neurons. Qhov tseeb, oodles ntawm txoj hauv kev kom tau cov ketones nyob rau hauv qhov ntawd los txhawb koj lub hlwb. Cov ketones tau siv rau hauv mitochondrial matrix (ib daim nyias nyias hauv koj cov roj teeb ntawm tes) uas ua rau lub zog.
Thiab ntawm no yog qhov kuv xav kom koj tau txais thiab. BBB siv zog los ntawm ketones thiab. Cov hlwb me me uas ua rau BBB sim ua rau lawv tus kheej ketone lub zog txhua lub sijhawm. Thiab yog tias koj nyob rau hauv kev noj haus ketogenic cov hlwb yuav rov ua kom muaj zog lawv yuav tsum tau ceev cov junctions uas yuav tsum tau ua kom BBB muaj zog thiab tsis zoo.
Kuv puas tau hais tias lub hlwb xav tau ntau lub zog? Zoo nkauj heev uas muaj txoj hauv kev kom tau txais lub zog nws xav tau uas tsis tas yuav siv zog ntxiv. Txoj cai? Nws yog hom zoo li cov nyiaj tau los passive es tsis txhob yuav mus rau hauv kab lis kev cai hustle. Kuv txhais tau tias, peb tuaj yeem tau txais cov GLUT receptors ua haujlwm dua thaum kawg thaum peb kho tau zoo. Tab sis peb yeej tsis mus rau hauv peb txoj kev kho yog tias peb tshaib plab lub hlwb nyob rau lub sijhawm no. Nws tsuas yog yuav mus txuas ntxiv cov txheej txheem neurodegenerative mus ntxiv. Raws li qhov nyiaj tau los, ketone lub cev kuj tseem txhim kho GLUT1 kev ua haujlwm, thiab GLUT1 yog tus thauj khoom uas pab cov piam thaj mus rau qhov twg.
Ketones yog anti-inflammatory
Peb tsuas yog tsis muaj cov tshuaj uas muab tib theem ntawm cov tshuaj tiv thaiv kab mob kom nyab xeeb lossis ua tau zoo raws li kev noj haus ketogenic.
Cov kev kho mob zoo ntawm cov tshuaj loj-spectrum anti-neuroinflammatory yog txwv los ntawm lawv cov kev mob tshwm sim tom qab kev tiv thaiv ib ntus.
JANIGRO, D. (2022). Cov teebmeem ntawm Ketogenic noj zaub mov ntawm cov ntshav-Brain Barrier. Kev Noj Qab Haus Huv Ketogenic thiab Kev Kho Mob Metabolic: Txhim Kho Lub Luag Haujlwm hauv Kev Noj Qab Haus Huv thiab Kab MobIb., 346., 355
Thaum muaj kev tiv thaiv kab mob ntev, muaj kev puas tsuaj uas ua rau lub hlwb thiab BBB. Qhov no ua rau mob thiab kev ntxhov siab ntxiv rau lub cev hauv kev sim ua kom muaj kev sib tshuam nruj hauv BBB. Qhov mob no tuaj yeem ua rau cov kab mob vascular tseem ceeb uas yog ib feem ntawm BBB. Nws tuaj yeem ua rau glial thiab astrocytes puas. Kev noj haus ketogenic txo qis kev mob. Cov ketones tsim los ntawm kev noj zaub mov ketogenic coj tus cwj pwm zoo li cov cim qhia, qhia cov noob koom nrog hauv kev mob ntev kom tig lawv tus kheej tawm. Muaj txiaj ntsig zoo rau kev pab BBB me me kom rov qab kho, tswj nws txoj kev ncaj ncees thiab ua haujlwm, thiab ua kom nws kho tau zoo yog tias koj nug kuv.
Tam sim no rov qab mus rau cov qauv vascular. Muaj ntau cov dementias uas muaj cov kab mob vascular. Ketones nce cerebral ntshav ntws uptake thiab qhov no nce ntshav txaus thiab siv cov pa oxygen yog xav tias yuav pab txhawb rau cov ntaub ntawv zoo neuroprotective los ntawm ketone lub cev. BBB leaky yog ib qho etiological hauv qee qhov dementias (piv txwv li, Alzheimer's) thiab nws tau xav tias cov txiaj ntsig pom nrog cov khoom noj ketogenic hauv cov neeg no yuav yog ib feem yog vim kev txhim kho BBB. Qhov kev xav tias ketones txhim kho neurovascular muaj nuj nqi hauv dementias yog thaj chaw tam sim no ntawm kev tshawb fawb.
Raws li yog tias tag nrho cov no tsis muaj laj thawj txaus rau kev siv cov khoom noj ketogenic los pab kho lub hlwb tsis zoo, ketones pab tsim ntau cov proteins uas BBB siv los kho cov kev sib tshuam uas tau txais los, pib nrog.
Ntxiv Options
Vim kuv ntseeg tias koj muaj cai paub txhua txoj hauv kev uas koj tuaj yeem hnov zoo dua, kuv yuav sau qee cov tshuaj uas tau siv uas muaj ntau theem ntawm cov pov thawj ntawm kev txhim kho BBB. Tab sis cia kuv ua kom meej meej tias kuv tsis xav tias qhov no yog qhov chaw ze li txias lossis zoo rau kev kho BBB raws li kev noj zaub mov zoo ketogenic. Tsis muaj ib qho ntawm cov tshuaj no kho cov tshuaj insulin. Tsis muaj ib qho ntawm cov no yog lwm qhov chaw roj rau lub hlwb. Qee qhov no tuaj yeem txhim kho kev ua haujlwm thiab cov ntshav ntws mus rau cov hlwb epithelial thiab endothelial, thiab qee qhov tuaj yeem muab qee qhov kev ua kom muaj zog antioxidant kom koj tuaj yeem sim ua si nrog oxidative kev nyuaj siab.
Koj puas yuav tau txais qee qhov BBB kho los ntawm cov tshuaj no? Yog, koj yuav. Tsuav yog qhov neurodegenerative cascade koj tau mus tsis muaj lub zog ntau dhau. Tab sis yog tias koj BBB permeability yog los ntawm mob stroke lossis TBI, lossis cov txheej txheem dementia thaum ntxov, cov no tsis muab cov roj hluav taws xob uas koj lub hlwb xav tau los tawm tsam lub hlwb hypometabolism. Cov tshuaj no tsis muab cov micronutrients txhim kho lossis txawm tias macronutrients rau kev saib xyuas thiab kho kom zoo rau lub hlwb thiab BBB muaj nuj nqi.
Yog tias koj mob siab txog kho koj lub hlwb, tsis txhob ntshai ua qhov koj tab tom xav yog qhov nyuaj heev. Kuv cog lus rau koj, tias kev kawm yuav ua li cas siv thiab txhawb nqa kev noj haus ketogenic tsis yog yuav luag nyuaj li muaj lub hlwb tsis ua haujlwm. Lub hlwb uas ua rau koj tsis txaus siab rau lub neej.
Lub paj hlwb uas muaj kev ntxhov siab tas li nrog cov teeb meem kev xav thiab teeb meem nco?
YOG HAIV NEEG. Txhua. Ib leeg. Hnub.
Kev noj zaub mov ketogenic yog qhov kev kawm nkhaus thiab koj tsim nyog tau txais kev txhawb nqa hauv kev siv nws. Tab sis kuv cog lus rau koj, raws li ib tug neeg uas tau rov qab los ntawm kuv lub hlwb, nws tsis yog yuav luag nyuaj li koj tab tom xav. Koj twb dhau ib qho nyuaj tshaj plaws. Kev noj zaub mov ketogenic yooj yim hauv kev sib piv.
Cov khoom noj uas tuaj yeem pab kho BBB suav nrog cov roj ntses, Ginko Bilboa, vinpocetine, alpha-lipoic acid, glutathione (tau liposomal lossis tseem ceeb precursors, kawm vim li cas no), thiab resveratrol.
Qee zaum kuv yuav siv qee qhov ntxiv rau kev noj haus ketogenic raws li kev kho mob ntxiv, tab sis kuv tsis siv lawv tus kheej los kho BBBs lossis lwm qhov hauv lub hlwb. Thiab yog li ntawd, kuv tsis paub qhov tseeb npaum li cas uas tib neeg siv yog tias lawv siv cov no ua thawj txoj kev kho rau lub hom phiaj no. Tab sis dua, koj tuaj yeem tshawb nrhiav cov kev hloov pauv no rau koj tus kheej kho.
xaus
Hauv Txoj Haujlwm Pabcuam Lub Hlwb Fog Kuv qhia, peb siv cov khoom noj ketogenic, kev noj zaub mov zoo rau tus kheej, thiab kev cob qhia rau kev siv tshuaj kho mob uas pab kho tus kab mob BBB thiab pab tib neeg ua lub neej zoo tshaj plaws. Vim cia peb ua siab ncaj. Koj ua neej li cas? Los ntawm koj lub hlwb. Koj tsis tas yuav nyob nrog cov tsos mob ntawm lub paj hlwb, tsis hais seb yog vim li cas lossis kev kuaj mob. Tsuas yog vim koj tus kws kho mob tsis quav ntsej koj cov lus tsis txaus siab txog koj qhov tsis muaj peev xwm ua kom pom tseeb, nco txog tej yam, lossis tswj koj lub siab tsis tau txhais hais tias tsis muaj kev kho mob zoo.
Kuv zoo siab los pab koj kawm txhua yam uas koj tuaj yeem ua tau zoo dua!
References
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